Regulation of pathogenesis and immunity in helminth infections
نویسندگان
چکیده
منابع مشابه
Regulation of pathogenesis and immunity in helminth infections
Helminths are multicellular eukaryotic parasites that infect over one quarter of the world's population. Through coevolution with the human immune system, these organisms have learned to exploit immunoregulatory pathways, resulting in asymptomatic tolerance of infections in many individuals. When infections and the resulting immune responses become dysregulated, however, acute and chronic patho...
متن کاملImmune Regulation during Helminth Infections
Helminth is a nonphylogenetic term that refers to multicellular animals (or metazoans) that have adopted a parasitic lifestyle in mammalian hosts. They are more commonly referred to as parasitic worms. These worms generally (with the exception of Strongyloides stercoralis) cannot replicate within the host, and they have evolved distinct methods to co-exist with their host through the activation...
متن کاملHelminth infections and host immune regulation.
Helminth parasites infect almost one-third of the world's population, primarily in tropical regions. However, regions where helminth parasites are endemic record much lower prevalences of allergies and autoimmune diseases, suggesting that parasites may protect against immunopathological syndromes. Most helminth diseases are spectral in nature, with a large proportion of relatively asymptomatic ...
متن کاملThe Mannose Receptor in Regulation of Helminth-Mediated Host Immunity
Infection with parasitic helminths affects humanity and animal welfare. Parasitic helminths have the capacity to modulate host immune responses to promote their survival in infected hosts, often for a long time leading to chronic infections. In contrast to many infectious microbes, however, the helminths are able to induce immune responses that show positive bystander effects such as the protec...
متن کاملPregnancy and helminth infections
It has been proposed that helminth infection may be particularly detrimental during pregnancy, through adverse effects on maternal anaemia and on birth outcomes, and that anthelminthic treatment during pregnancy will therefore be particularly beneficial. However, the few treatment trials that have been conducted have given, but little support to this notion and further trials in settings of nut...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2009
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.20091903